201 coronavirus strains from the NCBI protein database were analysed for furin cleavage sites present on their spike proteins.
Cleavage sites were found in 44 of them, with 17 hosted by bats and 27 by other mammals...including 1 raccoon dog?
Do tell.
đź“Śhttps://www.biorxiv.org/content/10.1101/2023.02.05.527216v1
Introduction Deciding when to release a new primer scheme is always a difficult decision because we want continuity but don’t want genomes with dropouts caused by primer problems. ARTIC v4/4.1 has been the recommended scheme for about 8 months now and as with v3 before it there are now a number of primers which have stopped working for many of the current circulating Omicron sublineages so we think now is the right time to recommend changing to the v5 scheme. Version 5 has actually been in dev...
Science blogs have been around for at least 20 years and have become an important part of science communication. So are there any fundamental issues that need fixing? Barriers to Entry Blogging platforms are mature at this point, and the technology is not imposing barriers to entry for most people.
“The #fediverse is like #email.”
Yes.
Now read this and understand it:
“I have been self-hosting my email since I got my first broadband connection at home in 1999 … But my emails are just not delivered anymore. I might as well not have an email server.
Email is now an oligopoly, a service gatekept by a few big companies which does not follow the principles of net neutrality … I lost. We lost. One cannot reliably deploy independent email servers.“
Via @cancel
Many companies have been trying to disrupt email by making it proprietary. So far, they have failed. Email keeps being an open protocol. Hurray? No hurray. Email is not distributed anymore. You just cannot create another first-class node of this ne
Our commentary article on Scott Hemsley’s #Science paper on their strategy to achieve a #universal influenza #mRNA vaccine is now out in @SciImmunology
👇🏼
Multiplexing mRNAs builds a “broad-immunity wall” against the flu
This could be a hugely important step taken in implementing genomics into routine Clin micro. These are the “boring” bits we don’t tend to think of but that are absolutely essential
The implementation of genomics for identification and surveillance of antimicrobial resistance (AMR) in clinical laboratories remains challenging. Here, Sherry et al. present a bioinformatics platform for detection of AMR determinants from whole-genome sequencing data, suitable for clinical and public-health microbiology reporting.
Reduced my twitter usage by >90% over past couple of months
The main way I interact with it now is by following 20 or so accounts of folks not on mastodon via RSS in Feedly, turns out that set of accounts produce 90% of the posts I want to see but combined they post <5 tweets per day on average.
also no more scrolling worried you missed something important
Also, now I check my feedly more regularly, which is probably a much healthier way of following the literature
Ben Pierce
Scalene
Martin Fenner
Aral Balkan
David R. Martinez
Alanmcn1
Alex Crits-Christoph
Janel Comeau