Luis Pedro Coelho

111 Followers
87 Following
38 Posts

If you missed my presentation at #BOSC2024, I just put up a version on YouTube

Paper at: https://doi.org/10.1371/journal.pcbi.1011920

https://youtu.be/yCgvvVQJE9I

For long-term sustainable software in bioinformatics

Extremely Open Science Stream

YouTube

Nice N&V Forum by @JakobWirbel, Ami Bhatt, Alexander Probst discussing how this study and the related Rodríguez del Río et al. provide insight into the vast structural and functional diversity of previously unknown microbial protein families

https://www.nature.com/articles/d41586-024-00077-w

@LBNLBioSci @apcamargo @BorkLab @luispedro @alvarordr

The journey to understand previously unknown microbial genes

Ways to find and investigate previously unidentified microbial genes.

New experiment: I will work on a project (starting question: what antibiotic resistance genes co-occur in genomes/metagenomes and does it matter?) completely in the open

Everyone is welcome!

First stream is on Monday/Tuesday (depending on your timezone)

https://youtu.be/0aX6b9z5uNo

Extremely Open Science Part 1 : introduction

YouTube
A new preprint from the lab of @luispedro in collaboration with our group, making use of our SPIRE database of global microbiome data to identify 965 million non-redundant small open reading frames (<100 amino acids) https://www.biorxiv.org/content/10.1101/2023.12.27.573469v1?med=mas
New video: "The GMGC as a window into the global microbiome" on YouTube
https://youtu.be/L7YWtYVoI8U
The GMGC as a window into the global microbiome

YouTube
We biology geeks may sound elitist when we use scientific names instead of common names, but we're really just trying to avoid this:

powerful datavis can be simple and non-graphical.

here's a project of mine from a good while ago: "autocomplete" for passwords, based on all passwords extracted from the "collection leaks".

https://passwords.yetzt.me/

Password

metaMIC: reference-free misassembly identification and correction of de novo metagenomic assemblies https://doi.org/10.1186/s13059-022-02810-y #microbiology #bioinformatics
metaMIC: reference-free misassembly identification and correction of de novo metagenomic assemblies - Genome Biology

Evaluating the quality of metagenomic assemblies is important for constructing reliable metagenome-assembled genomes and downstream analyses. Here, we present metaMIC ( https://github.com/ZhaoXM-Lab/metaMIC ), a machine learning-based tool for identifying and correcting misassemblies in metagenomic assemblies. Benchmarking results on both simulated and real datasets demonstrate that metaMIC outperforms existing tools when identifying misassembled contigs. Furthermore, metaMIC is able to localize the misassembly breakpoints, and the correction of misassemblies by splitting at misassembly breakpoints can improve downstream scaffolding and binning results.

BioMed Central

Hi, I guess this is my #introduction? I'm a Bioinformatics student interested in machine learning, genomics, and in vivo gene therapy. When I'm not doing science, I'm usually obsessing over your dog, being a coffee snob, running my beer club, or I'm at the hockey rink.

Now, I promise I'm good at computer science, but my skills seem to be limited to science and I am not understanding how on EARTH to log onto this platform directly from the app 😂