This will be one of the subjects of the book I have coming out next month, so it's interesting to see that the first major study of its kind has proven that cats fed dry food versus wet food have much higher rates of diabetes, kidney disease, and fatty liver disease.

Cats on dry kibble diet have significantly different microbiome than those on canned wet food - npj Veterinary Sciences
Domestic cats (Felis catus) are understudied regarding how commercial diets impact their gut microbiomes. Here, we reanalyzed the 16S rRNA gene (V4) amplicon sequencing Kittybiome dataset, using new tools and techniques. Results demonstrated significant microbial composition differences between cats eating commercial dry kibble diets and those eating canned wet food. Kibble-fed cats showed enriched Prevotella, Bifidobacterium, and Megamonas amplicon sequencing variants (ASVs), linked to carbohydrate metabolism and metabolic disease.







