Nabil-Fareed Alikhan

1.6K Followers
941 Following
1.3K Posts

We're now running mastodon 4.5.9

As always, let me know if things are not working as expected.

If you have some spare dosh, please donate to https://opencollective.com/mstdnscience

All proceeds go to running the server, our books are open for your scrutiny.

mstdn.science - Open Collective

Mastodon community (instance) of scientists and enthusiasts

💡 Support mstdn.science with a Financial Contribution! 💡

mstdn.science exists through contributions by folks like you. If you're not skint from the season's festivities, consider making a regular contribution to https://opencollective.com/mstdnscience . If we can manage another £60 / month, the instance would be self sufficient!

mstdn.science - Open Collective

Mastodon community (instance) of scientists and enthusiasts

Could some clarify what it means go medieval on ones ass? Like specifically what would that entail and what equipment would be needed ?

Join the Galaxy Training Academy 2026 and hear from leaders across computational biology, including guest speaker Aaron Quinlan.

Known for his work in computational genomics and widely used open-source tools like BEDTools and Mosdepth, Aaron will be featured in our daily podcast-style interview series during GTA.

Join us May 18–22 for a free, virtual week of learning with the Galaxy community, and stay tuned as we reveal more guest speakers.

Learn more and register: https://gxy.io/GTA2026-info

Oh yeah. Support the instance.

https://opencollective.com/mstdnscience

omg. I was using MS word --- and i forgot to save a doc!

I have become too lazy with autosaving via google docs.

!! rookie mistake

BRIG v1.1.1 release.

There's some minor quality of life changes but the key thing is fixing the GC Skew and Content graphs for small reference sequences (plasmids), from the chunky and blocky histogram, we now have a much smoother solution.

Download from github:

https://github.com/happykhan/BRIG/releases

Download from sourceforge:

https://sourceforge.net/projects/brig/files/v1.1.1/

Host read removal sounds simple. It's not. 🧫Ep. 151 of microbinfie: we talk with Bede Constantinides about Deacon — why alignment-based approaches fall short, the sensitivity/specificity tradeoff, and what it takes to remove host reads at scale. Part 1 of 2.

https://soundcloud.com/microbinfie/151-deacon-part-1

151 - Deacon part 1

In this Software Deep Dive episode, we talk with Dr. Bede Constantinides (University of Birmingham) about Deacon, a tool for removing host DNA reads from metagenomic datasets. We discuss why host read

SoundCloud

the web application is available at :

https://brigx.genomicx.org/

I would be interested to hear feedback regarding bugs or any unexpected behaviour, any suggestions for the user interface, or any features you feel would be useful .

BRIGX - Browser-Based Ring Image Generator

Circular comparative genome visualization tool running entirely in your browser

Been working on a browser version of BRIG. No install. Interactive. Looking for beta testers; message me if you're interested.

BRIG Is a visualisation tool that draws circular genome comparison plots. The user provides a reference genome and a set of query genomes which are aligned using BLAST. Genomes are bacteria sized (< 20Mbp). Colour gradient shows alignment identity. Users can also provide tables of coordinates for their own annotations on the plot.