#introduction I am a new Bioinformatics data wrangler and a contractor for NCBI, trying to help them to develop the Comparative Genomics Resources. Until earlier this year, I studied mostly genomes of "extremophyte" plants that thrive under harsh environments using #comparativegenomics approaches: e.g. to identify lineage(s)-specific modifications of gene copy numbers and gene regulatory networks among the "extremophytes" and their close relatives.

#introduction I'm Carl Boettiger. I'm a theoretical ecologist and data scientist at Berkeley. I'm interested in #rstats, #openscience, #opensource #python, #linux, & #teaching. Feels lovely to have a timeline instead of an algo once more, & so many friends here!

Dear followers. I'm moving to Mastodon, I won't interact via Twitter anymore. But happy to keep tooting at @CastellanoED. I've enjoyed tremendously learning from you, feeling you and loling with you. See you at the end of the tunnel.

I want to inaugurate my science Mastodon with this recent preprint with Lindi Wahl and Ryan Gutenkunst. We show that mutation rate modifiers are more likely to fix when they are also coupled with mutation bias modifiers that reverse the mutation bias of the original wild type modifier. In the rare case where all mutation types have the same mutation rate then this magnifying effect does not occur. https://doi.org/10.1101/2022.09.27.509708