Anna Gloyn

@annagloyn
60 Followers
41 Following
13 Posts
Stanford Peds Endo & Genetics 🧬🔬🧫🤿🚴‍♀️🎿
Websitehttps://med.stanford.edu/genomics-of-diabetes.html
Stanford Profilehttps://profiles.stanford.edu/anna-gloyn
InterestsDiabetes, Genomics, Islets, Women in science
Outside work🤿🚴‍♀️🎿
Anna Gloyn on Twitter

“Congratulations to @nkrentz & #katiaMattis on this tour to force at #T2D #GWAS #RREB1 locus. Thanks to collaborators @bcellorg & @denhoedm on taking us from 🐟through 🧫back to humans. @StanfordDRC @StanfordPedEndo https://t.co/qbOq1g9hWF”

Twitter

A wonderful study carried out on the EndoC-betaH1 #cellline (https://cellosaurus.org/CVCL_L909): "A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk":

https://www.nature.com/articles/s41588-022-01261-2

Cellosaurus cell line EndoC-betaH1 (CVCL_L909)

$id in Cellosaurus, a cell line database, cell line catalogue, cell line ontology

We published a paper

"Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease" 1/

https://authors.elsevier.com/c/1gIGbL7PXiquv

DOI: https://doi.org/10.1016/j.cell.2022.11.028

A great paper from @annagloyn and colleagues! Happy we were able to contribute.

"A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk" Nature Genetics.

https://t.co/wD8SreMFzQ

Statue of Henrietta Lacks to replace Robert E Lee https://www.bbc.co.uk/news/world-us-canada-64059050
Statue of Henrietta Lacks to replace Robert E Lee

She will be honoured decades after cells taken without her consent helped revolutionise medicine.

BBC News
Looking forward to reading this, congrats to the team!
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RT @annagloyn
🚨An early Christmas Present👇
Congratulations to @antje_rottner on this tour de force - despite 700M pesky human cells, a transatlantic lab move & a global pandemic she delivered 580 genes which influence how much insulin human beta-cells contain. https://rdcu.be/c12EO
https://twitter.com/annagloyn/status/1605617847798878209
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk - Nature Genetics

A genome-wide CRISPR knockout screen in the human EndoC-βH1 pancreatic beta cell line identifies 580 regulators of intracellular insulin content. Loss of CALCOCO2 perturbs insulin granule homeostasis in pancreatic beta cells.

Nature
What a way to end #2022! Excited that our genome-wide CRISPR LOF screen in human beta cells for insulin protein content is finally out. Resilience from Dr Antje Rottner with pesky human cells, a transatlantic lab move and a pandemic.... We did it!! https://rdcu.be/c12EO
Antje Rottner on Twitter

“It is finally out 🥳! Proud and excited to present my @UniofOxford PhD work and our genome-wide #CRISPRscreen in human pancreatic beta-cells @NatureGenet after more than 6 years of hard work! @annagloyn Highlight 🧵below /1 https://t.co/GKNUSTegau”

Twitter