| Website | https://med.stanford.edu/genomics-of-diabetes.html |
| Stanford Profile | https://profiles.stanford.edu/anna-gloyn |
| Interests | Diabetes, Genomics, Islets, Women in science |
| Outside work | 🤿🚴♀️🎿 |
| Website | https://med.stanford.edu/genomics-of-diabetes.html |
| Stanford Profile | https://profiles.stanford.edu/anna-gloyn |
| Interests | Diabetes, Genomics, Islets, Women in science |
| Outside work | 🤿🚴♀️🎿 |
A wonderful study carried out on the EndoC-betaH1 #cellline (https://cellosaurus.org/CVCL_L909): "A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk":
We published a paper
"Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease" 1/
A great paper from @annagloyn and colleagues! Happy we were able to contribute.
"A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk" Nature Genetics.
Check out this fantastic commentary on precision medicine by @[email protected] @[email protected] http://doi.org/10.1038/d41586-021-02401-0 an inspiration for our study!
And the shoutout https://twitter.com/EricTopol/status/1605349241773117440?s=20&t=wJbJ9TAQyE_ZIWOwgiXIUg by the one and only @[email protected] 🙌🏻
🐦🔗: https://twitter.com/IainSForrest/status/1605589974560018433
A genome-wide CRISPR knockout screen in the human EndoC-βH1 pancreatic beta cell line identifies 580 regulators of intracellular insulin content. Loss of CALCOCO2 perturbs insulin granule homeostasis in pancreatic beta cells.