Posting on behalf of the @ncfg -
In our latest Interesting Fact Post learn about Mitochondrial Glycoproteins!
Think #mitochondria don't have #glycoproteins? Think again! New research shows O-GlcNAc modifications are key to: Energy Brain Health, Development
Read: https://research.bidmc.org/ncfg/blog/25-facts-about-mitochondrial-glycoproteins
RE: https://mastodon.social/@ncfg/115899898770086120
Glycans probably have more "copies/cell" than proteins and changes in glycosylation could potentially be remarkable biomarkers for diseases as well as targets for therapeutics. This post explores the abundance of glycans on the cell surface and it is worth a read to recognize these biomolecules.
#glycans hashtag#glycosylation hashtag#biomolecules hashtag#proteins hashtag#glycoproteins
Have you heard of sugar alcohols, such as erythritol, sorbitol, mannitol and xylitol? These are commonly used as artificial sweeteners. Learn more about these interesting small sugars and where they are found in our latest blog post, https://research.bidmc.org/ncfg/blog/23-facts-about-sugar-alcohols
#glycans #glycotime #glycosylation #science #artificialsweeteners
📢New article alert! 'Blood group O expression in normal tissues and tumors', just published in FEBS Journal, highlights findings using our lamprey-derived monoclonal antibodies towards specific H antigen epitopes. Check out the paper to see the interesting and surprising staining seen in different cells and tissues: https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.70172
Explosions, allergies, & more! 🤯 Polysaccharides are more surprising than you think!
Read our latest interesting facts about Dangerous Carbohydrates: https://research.bidmc.org/ncfg/blog/18-facts-about-dangerous-carbohydrates
📢 Our latest work describing a new versatile click chemistry glycan linker which enabled us to create glycan derivatives for use in microarrays, Luminex (bead based arrays) and ELISA assays.
Check it out in @acs.org ACS Central Science https://doi.org/10.1021/acscentsci.4c02124
In the latest interesting facts about #glycans, we take a look at two tiny #glycolipids which are critical for life.
Read the full post at: https://research.bidmc.org/ncfg/blog/17-facts-about-two-tiny-glycolipids-essential-life
For more interesting facts: https://research.bidmc.org/ncfg/interestingfacts/interesting-facts-about-glycans
We have an opening! If you are looking for a great postdoc fellowship in Boston - then check out this opportunity to work on antibody production against glycan antigens:
https://research.bidmc.org/ncfg/careers/postdoctoral-research-fellowship-immunology-and-glycoscience-cummings-lab-bidmc
Please re-share to spread the word
#glycotime #glycocareers #postdoc
Our latest blog on interesting facts about glycans we dig deeper into the UDP-glucuronic acid and glucuronyltransferases in the endoplasmic reticulum - which can be critical in drug metabolism.
Read at: https://research.bidmc.org/ncfg/blog/facts-about-udp-glucuronic-acid-and-glucuronosyltransferases-er
Keyhole Limpet Hemocyanin (KLH) is used to produce #antibodies and as an #immunostimulant. Interestingly 3-4% of it's weight is #carbohydrate.
In this month's interesting facts about #glycans we take a look at the unusual #glycosylation of KLH.
Read at: https://research.bidmc.org/ncfg/blog/facts-about-keyhole-limpet-hemocyanin-klh-and-its-unusual-glycosylation
NCFG