StefanBassler

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Predoc @TypasLab @EMBL & @iDEC2022 HQ interested in #ResistanceEvolution, #SystemsBiology and #Ageing with experience from @Harvard, @EPFL_en & @biozentrum
Check our new preprint on drug interactions in 3 Gram-positive bacterial species. Over 10,000 combinations with a plethora of novel synergies and unexpected activities of non-antibiotics against multi-drug resistant #Saureus. Heroic effort of @elisca
https://www.biorxiv.org/content/10.1101/2022.12.23.521747v1
One approach to tackle bacterial infections is to disrupt the integrity of the bacterial envelope with antibiotics. We set up a colour palette to quantify this process by eye which could be great for education.
@TypasLab @embl
https://www.embl.org/news/picture-of-the-week/spotlight-establishing-a-colour-palette-for-antibiotic-resistance/
Spotlight: Establishing a colour palette for antibiotic resistance | EMBL

To identify which drugs disrupt bacterial envelope integrity, the Typas group uses a molecule called chlorophenyl red-β-D-galactopyranoside.

EMBL