Monika Wolkers

138 Followers
173 Following
209 Posts
T cell immunologist who wants to understand physiological and pathological #T cell effector function. Great love for #RNA biology, #Sanquin, #OncodeInstitute

This is a many-years study, started by Marleen Van Loenen, continued by Rosa de Groot, and now analysed and written up by Suzanne Castenmiller and Nandhini Kanagasabesan, w supported by Aurélie Guislain and Benoit Nicolet, PhD

Great collaboration with the medical team from the AvL-NKI, with
Koen Hartemink, Kim Monkhorst, Alexander Veenhof, Egbert Smit en John Haanen

Supported by Sanquin Blood Supply Foundation funding and Oncode Institute

Now In press!!!

We came to the surprising conclusion that (contrary to what is reported for responsiveness to immunotherapy), the tumor reactivity of TIL products negatively correlates with the amount of B cell/ naive T cell infiltrates in the tumor.

We also have a hypothesis as to why that is.

Interested? Check it our!

https://lnkd.in/eWpdqvta

LinkedIn

This link will take you to a page that’s not on LinkedIn

@Green_Footballs

May I suggest getting a public library card?

I access almost all paywalled material for free via PressReader using my public library.

If you live in a red state, Brooklyn Public Library offers services to victims of GOP book bans & other attacks on literate citizenship. Ditto Boston Public Library.

@TatianaIlyina

I refuse to accept when it hits family life. Does it hurt my career? Don't think so. And if it does? Well, bad luck. They cannot complain about too few children in our society while making it impossible for women to combine work with family life. I must add: i was blessed with understanding colleagues. But culture changes from within. I also strongly believe it is important to show the next generation that a job does not mean sacrificing everything.

Sad news: Frans de Waal — Ig Nobel Prize-winning biologist who studied the many odd ways that monkeys and humans and other primates behave — has died. https://improbable.com/2024/03/16/sad-news-frans-de-waal-is-gone/
Sad news: Frans de Waal is gone

Frans de Waal has died. Among his smaller accomplishments was winning an Ig Nobel Prize in 2012, with colleague Jennifer Pokorny, for for discovering that chimpanzees can identify other chimpanzees…

Why are so many young people getting cancer? What the data say

Clues to a modern mystery could be lurking in information collected generations ago.

An experience of time tracking as a scientist https://www.nature.com/articles/d41586-024-00806-1
A year in the life: what I learnt from using a time-tracking spreadsheet

A low-tech solution helped Megan Rogers to increase her productivity and maintain a good work–life balance.

@cyrilpedia

Not sure i am happy with this. In the NL we already have this in place. Does it really help? I think

1) evaluation highly (and too much) depends on the writing style (not so much on the achievements themselves). And this type of writing TMO does not necessarily reflect how good a researcher is.

2) is even more difficult for the reviewer to extract the prime evaluation points

TMO a list would also allow to include non-classical achievements, parts of contribution, etc.
#ERC

Please find below our most recent pre-print. We studied the role of the RNA binding protein ZFP36L2 in effector T cells and found how it regulated the production of IFNgamma in late T cell responses and continuous activation with tumor cells (in vitro/in vivo). Happy reading!

https://www.biorxiv.org/content/10.1101/2024.02.09.579641v1.article-metrics

#Tcells #immunology #tumor #rna_binding_proteins #cytokines

As much as i am horrified about the neo-fascist developments in Germany, i am just very proud of the citizens of my home country to step up and clarify that the 'silent' majority absolutely does NOT support this AfD rubbish, and that it starts speaking up. I very much hope that this is just the start for a Europe wide- what do I say - world wide movement for stepping up!

https://www.tagesschau.de/inland/gesellschaft/demonstrationen-gegen-rechts-sonntag-100.html

Erneut Zehntausende bei Demonstrationen gegen Rechts erwartet

Nachdem am Samstag Hunderttausende Menschen in Deutschland gemeinsam für Toleranz und gegen Rechtsextremismus demonstriert haben, werden auch für den Sonntag wieder große Protestaktionen erwartet.

tagesschau.de