Mastodawn

Stavros Vagionitis May 4, 2023

RT @TzelepisLab
Pleased to see that our institute ⁦@SCICambridge⁩ is one of the @wellcome Discovery Award recipients! Well done to everyone involved! Exciting times ahead! https://www.cam.ac.uk/research/news/wellcome-awards-cambridge-ps18-million-for-two-discovery-research-platforms

Wellcome awards Cambridge £18 million for two Discovery Research Platforms

Cambridge has been awarded two of Wellcome’s eight new Discovery Research Platforms, the global charitable foundation announced today.

University of Cambridge

Stavros Vagionitis Apr 27, 2023

RT @UKDRI
An exciting new study led by Prof David Rubinsztein (UK DRI at Cambridge) reveals an HIV drug helps protect against build-up of toxic proteins in mouse brains, in 2 models of neurodegenerative disease🧠

HIV drug helps protect against build-up of dementia-related proteins in mouse brains

In a new mouse study, scientists led by Prof David Rubinsztein (UK DRI at Cambridge) have revealed that a repurposed HIV drug can restore the brain’s ability to clear out toxic proteins, which is impaired in Huntington’s disease and other forms of dementia. The research, published in the journal Neuron, offers clues to how the build-up of toxic proteins could in future be slowed or prevented in humans.

UK Dementia Research Institute

Stavros Vagionitis Apr 27, 2023

RT @DgnLab
(1/4) Happy to share our latest paper, uncovering the clonal dynamics of #microglia in brain development! Very cool findings part of the PhD of our fabulous @LiamBC1995, published in @CellReports

https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00436-9

Stavros Vagionitis Apr 26, 2023

I wonder what this is?? @MKBHD @elonmusk

Stavros Vagionitis Apr 25, 2023

RT @sangerinstitute
Happy #DNADay! Today marks 70 years since discovery of the double helix structure of DNA.

We celebrate everyone who is working to understanding the code of life. Thank you for your incredible contributions to science 🧬

Find out more about our work ⬇️

https://bit.ly/3HdbhZi

History of the Sanger Institute - Wellcome Sanger Institute

Timeline of the Sanger Institute's history

Stavros Vagionitis Apr 25, 2023

Happy #DNADay2023 everyone! Celebrating where it all happened with an illustration from @PDBeurope https://pdb101.rcsb.org/motm/23

PDB101: Molecule of the Month: DNA

Atomic structures reveal how the iconic double helix encodes genomic information

RCSB: PDB-101

Stavros Vagionitis Apr 24, 2023

RT @VarsityUK
Senior Science Editor, Suchir Salhan, discusses the diversity crisis in Cambridge Science https://www.varsity.co.uk/science/25395

There’s a Diversity Problem in Cambridge Science

Cambridge has a rich history of famous scientists, but maybe the way the Sciences are taught in the University needs to be rethought?

Varsity Online

Stavros Vagionitis Apr 22, 2023

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RT @ThoraKaradottir
Lab reunion for the 10 year anniversary of our first paper ~o~ Lundgaard et al 2013 https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001743. ~o~ https://t.co/IiCMpAGm8y
https://twitter.com/ThoraKaradottir/status/1649890030532415490

Neuregulin and BDNF Induce a Switch to NMDA Receptor-Dependent Myelination by Oligodendrocytes

Neuregulin switches oligodendrocytes between two modes of myelination: from a neuronal activity–independent mode to a myelin-increasing, neuronal activity–dependent, mechanism that involves glutamate release and NMDA receptor activation.

Stavros Vagionitis Apr 21, 2023

RT @ZucheroLab
What controls the morphology of #myelin sheaths to enable them to fine-tune conduction velocity? TL;DR: Calcium (Ca2+) signaling; a.k.a. nature’s ultimate multitasker! Read our new pre-print to find out more, led by grad student @_manasi_iyer_! 🧵👇(1/n)

Stavros Vagionitis Apr 21, 2023

RT @Pluchinolab
Delighted to have written together with @CamNeuro
PhD student Nathi Prasad this short piece in support of Mayrhofer et al. @JExpMed 2023 showing material transfer between OLs and neurons in the central nervous system

https://rupress.org/jem/article/220/7/e20230489/214049/Oligodendroglia-to-neuron-material-transfer-lights?searchresult=1

Oligodendroglia-to-neuron material transfer lights up the mouse CNS | Journal of Experimental Medicine | Rockefeller University Press

Intercellular material transfer in the central nervous system (CNS) supports neuronal survival and activity. Mayrhofer et al. characterize extensive regionally