BenedicteCallan

@BeneCal
524 Followers
1,016 Following
2K Posts
Sci, Tech & Health policy nerd.

A federal judge ruled Medicare can negotiate prices for prescriptions this fall

The US pays 2.4x the avg of industrialized nations for prescriptions

Brand name drugs make up 84% of total drug costs in the US—but account for only 8% of drugs sold

Tecartus +$25000 inc over 1yr
Fluconazole +1101% inc over 1yr
Lisinopril +539% inc over 1yr

Pfizer $10B revenue '22
Johnson & Johnson $95B revenue '22

You start working on a cure for high drug prices

We'll start working on a cure for MBAs

On my phone the top story at the NYT is Trump's civil trial. The 8th story is the awarding of the Nobel to Kariko and Weissman, two people who made it possible to quickly immunize billions during a global pandemic. #1 a crook's lifelong saga of corruption and lies, #8 the resilience of scientists whose work was for years seen as marginal and who nevertheless persevered to advance science and medicine.
@chargrille @jalefkowit@octodon.social I get the impression a lot of that money went to hiring teachers and possibly remote learning technologies. But I couldn't find a good accounting. CRS has this document about the funds but it's not very informative. https://crsreports.congress.gov/product/pdf/R/R47027
@NicoleCRust What great news!

Congrats to my colleagues Katalin Kariko and Drew Weissman on the Nobel Prize!

My favorite part of this news is knowing that more people (including kids) will get to hear and be inspired by the story behind the science and scientists (especially Kariko).

https://penntoday.upenn.edu/news/katalin-kariko-and-drew-weissman-penns-historic-mrna-vaccine-research-team-win-2023-nobel

Katalin Karikó and Drew Weissman, Penn’s historic mRNA vaccine research team, win 2023 Nobel Prize in Medicine | Penn Today

The highest honor was bestowed for foundational discoveries that gave the world a vaccine to fight the COVID-19 pandemic.

Penn Today
Covid-19: la nouvelle campagne de vaccination, avancée de 15 jours, débute ce lundi

VIDÉO - Dans un contexte de circulation plus active du virus, la campagne de vaccination contre le Covid-19 initialement prévue le 17 octobre, est avancée au 2 octobre.

BFMTV

This thread (by a compsci PhD I think) helps explain why we need 3 antigen tests over 4 days to get a reliable diagnosis of infection, and why you are highly, highly likely to get a false negative test if you only test once - even if you have symptoms.

The tests rely on detecting nucleocapsids, which is good for their longevity as the virus continues its blistering pace of mutation, but bad for timely diagnoses.

Sadly, it doesn’t mention FDA guidance to test 3 times.
https://progressives.social/@Wikisteff@mastodon.social/111143881142304564

Steffen Christensen (@Wikisteff@mastodon.social)

Attached: 1 image However, the tests need nucleocapsid protein there to detect, which only appears later on in infections at high volumes. Early on in an infection, tests don't work great. Symptoms usually appear on Days 2, 3, and 4 after infection; however, RAT tests only have about a 34% sensitivity on Day 3, rising to 67% on Day 4, and 80% on Day 5 for symptomatic individuals. That's because most people have antibodies now, and our immune systems respond at lower doses than RAT tests.

Mastodon

Good morning, fedi. Do you know anyone currently studying (or carefully searching for) coordinated influence campaigns on federated networks?

ETA: I have a reasonably good sense of who the people are who study this elsewhere, but I’m wondering if I’ve missed any known and especially homegrown/born on-fedi work on influence campaigns in federated spaces. Many thanks!

Net Neutrality Returns to FCC Agenda Under Democrat Majority, and Immediately Draws Criticism
#Variety #News #Fcc #NetNeutrality

https://variety.com/2023/digital/news/net-neutrality-fcc-agenda-democrat-criticism-1235736049/

Net Neutrality Back on FCC Agenda Under Democrat Majority, Draws Fire

FCC Chairwoman Jessica Rosenworcel wants to re-establish net neutrality rules that would bar internet providers from blocking or degrading access.

Variety

NIH asking for public comment on potential changes to the Policies for Oversight of Dual Use Research of Concern (DURC) and the Potential Pandemic Pathogen Care and Oversight (P3CO) Policy Framework. If you do work with pathogens or potential pathogens you may want to take a look at the proposed language. The rules could apply to any US institution or foreign institutions that accept US gov't funding.

https://www.niaid.nih.gov/grants-contracts/share-your-views-proposed-revisions-biosafety-policy

Share Your Views on Proposed Revisions to Biosafety Policy

Respond to a request for information on Potential Changes to the Policies for Oversight of Dual Use Research of Concern and the Potential Pandemic Pathogen Care and Oversight Policy Framework by October 16, 2023.