Accelerate.EU

@Accelerate_EU
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The goal of Accelerate.EU is to establish a stable and reliable cross-European supply chain for 211 At, ensuring broader availability and access to this promising treatment. The project also aims to develop a cutting-edge cyclotron and to enable the deployment of a distribution network to produce 211At for hospitals.
Acceletate.EU is supported by the Innovative Health Initiative Joint Undertaking (IHI JU) under grant agreement No [10173001].

Great to have been at the Theranostics World Congress with the Accelerate.EU consortium.

We were happy to share the progress made on Astatine-211 and targeted alpha therapies.

#AccelerateEU #Astatine211 #Theranostics #TargetedAlphaTherapy #NuclearMedicine #IHI

Attending Theranostics World Congress? Meet members of the Accelerate.EU consortium to discuss our progress in developing Β²ΒΉΒΉAt-based alpha radiotheranostic.

πŸ“Œ Poster presentation
β€œRegulatory Challenges for Novel Alpha Therapies: A Call for Harmonization”
Presented by Prof. Antero Abrunhosa.

Let’s connect and exchange on the future of alpha therapies.

π–π‘πšπ­ 𝐚𝐫𝐞 𝐭𝐑𝐞 𝐚𝐝𝐯𝐚𝐧𝐭𝐚𝐠𝐞𝐬 𝐨𝐟 𝐀𝐭-211?

At-211 emits a single Ξ±-particle with high Linear Energy Transfer (LET) (~100 keV/Β΅m), leading to 𝐑𝐒𝐠𝐑π₯𝐲 π₯𝐨𝐜𝐚π₯𝐒𝐳𝐞𝐝 𝐚𝐧𝐝 𝐞𝐟𝐟𝐞𝐜𝐭𝐒𝐯𝐞 𝐃𝐍𝐀 𝐝𝐚𝐦𝐚𝐠𝐞.

Moreover, the α-particles emitted by At-211 have a very short path length in tissue (50-100 ¡m), ensuring that radiation is concentrated within a few cell diameters, 𝐦𝐒𝐧𝐒𝐦𝐒𝐳𝐒𝐧𝐠 𝐨𝐟𝐟-𝐭𝐚𝐫𝐠𝐞𝐭 𝐞𝐟𝐟𝐞𝐜𝐭𝐬.

Learn more about the advantages of At-211 on our website: https://lnkd.in/eCysUBqv

Did you know that 1 in 6 breast cancer cases is classified as triple negative (TNBC)? This challenging subtype lacks effective therapeutic targets and leaves those affected with limited options and a dismal prognosis when metastatic.

Accelerate. EU, is pioneering an innovative approach: 211 Astatine-dual FAPi therapy. This groundbreaking treatment links a potent therapeutic isotope to a protein in the tumor microenvironment, leveraging molecular imaging and theranostics to advance care.

Let's take a moment to celebrate JΓ©rΓ΄me Harray remarkable dedication and leadership in making the Accelerate. EU project a reality!

Thank you for the countless hours and unwavering vision you’ve invested to make this project possible. We’re grateful to have you leading this initiative, paving the way for improved access to innovative #cancer treatments across Europe.

πŸš€ Accelerate. EU Program Kick-Off!

We were happy to bring together 17 leading European institutions and companies from 9 countries for a highly constructive kick-off meeting of the Accelerate.EU program. By blending academic expertise with industrial innovation, this initiative is set to make a real difference in improving access to radiotheranostics and innovative #cancer treatments.

ACCELERATE. EU is a project pioneering the development of novel radiotheranostic pairs featuring the alpha-emitting isotope #astatine-211 (211At) to target aggressive cancers like pancreatic, breast, and brain #cancer.
By combining innovative therapies with a new generation of compact cyclotrons, the project aims to enhance cancer treatment outcomes and make these advanced therapies more accessible in clinical settings.
Advancing cancer treatment is at the heart of Accelerate. EU.
By ensuring access to #211At across Europe and aligning research efforts, we’re moving towards more effective, targeted therapies. This is a key step in improving outcomes for people living with cancer.
Accelerate. EU will explore co-clinical approaches, where clinical studies run in parallel with preclinical studies, enhancing the ability to identify patients who are most likely to benefit from 211At therapy.
The Accelerate .EU collaboration brings together 17 leading European institutions and companies
across 9 countries, blending academic expertise with industrial innovation. The project is coordinated by @JulesBordet & @IBA_RadioPharma

πŸš€ EUR 16 Million Granted to Accelerate.EU to Advance Cancer Therapies in Europe!

It has officially launched with EUR 16 million in funding from the European Commission! Led by IBA and the Jules Bordet Institute, this project is all about making a real difference in cancer care by creating a reliable European supply chain for Astatine-211 (211At), a promising treatment for aggressive cancers.

With 17 partners across 9 countries, Accelerate.EU unites experts from academia and industry