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Transcriptomic analysis of muscle biopsies from IIM patients revealed key pathways and immune profile differences among phenotypes. Highlights monocyte involvement in muscle damage, with dermatomyositis showing complement and interferon signaling

In Arthritis & Rheumatology
https://loom.ly/JpuP7jY

New research suggests patients with axial spondyloarthritis who don't respond to secukinumab treatment may have an increased type 1 IFN signature and higher IL-17A producing cells. This calls for precision medicine

In Arthritis & Rheumatology
https://loom.ly/I9kmVHU

The presence of relaxing places to walk and infrastructure built for walking are associated with increased walking for leisure and walking near home, supporting the likelihood of patients walking for leisure near their homes 🚶‍♀️

In Arthritis Care & Research
https://loom.ly/SZ2VzxY

B and T cell subsets were interrogated in two types of lupus-prone mice: Baff-/- and Br3-/- NZM. Results suggest BAFF–BCMA & BAFF–TACI interactions in an SLE-prone host help drive clinical disease even under B cell depletion

In ACR Open Rheumatology
https://loom.ly/bnt8r2E

New study found Black women with systemic lupus erythematosus and limited health literacy had worse clinical outcomes, representing a particularly vulnerable population with significantly disparate health outcomes

In ACR Open Rheumatology
https://loom.ly/OvPaulo

What impact does family history have on risk of arthritis, osteoporosis, and carpal tunnel syndrome? New study identified increased risk in those with family history of these conditions

In Arthritis Care & Research
https://loom.ly/hnQRPVY

🎦 Narrated abstract on YT: https://loom.ly/LWloYws

People with autoimmune or inflammatory rheumatic diseases residing in rural areas were found to have higher post-COVID-19 two-year mortality in a large U.S. cohort after adjusting for background risk factors

In Arthritis Care & Research
https://loom.ly/BHTF4Tw

Novel findings on transposable element expression in systemic lupus erythematosus, which suggest expression of transposable elements contributes to SLE-related mechanisms in a cell- and phenotype-specific manner

In ACR Open Rheumatology
https://loom.ly/z0qvwfY

In people with erosive gout receiving urate-lowering therapy, higher baseline dual-energy CT measurement of monosodium urate crystal volume was associated with lower odds of gout remission after 2 years of treatment

In Arthritis Care & Research
https://loom.ly/I7oOu_M