"These findings suggest a fundamental mechanism by which cancer cells may evade apoptosis by exploiting Bcl-2’s ability to neutralize Bax through structural entrapment, even if excess Bax is present, either in response to treatment or natural death signals."

http://dx.doi.org/10.1021/acschembio.5c00913

#apoptosis #oncology #biochemistry #molecularBiology #biology #cancer