After 60+ years, the common diabetes drug metformin has been found to unexpectedly affect the brain.
A new study shows it targets the protein Rap1 in the ventromedial hypothalamus, activating SF1 neurons to help lower blood glucose — and it works at much lower concentrations in the brain than in the body.
Promising findings that could lead to better treatments for glucose control and possibly brain protection.

#Metformin #Diabetes #BrainHealth #MedicalResearch #Prediabetes

https://www.sciencealert.com/after-60-years-diabetes-drug-revealed-to-unexpectedly-affect-the-brain