Researchers identified a previously unappreciated subtype of helper T cells that migrate to the lungs during infection and produce the protein HIF-1α to orchestrate a localized, coordinated immune defense.
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https://www.sflorg.com/2026/03/imgy03242601.html
Local immune coordination in the lung reveals a new layer of defense

The lung maintains its own community of immune cells capable of mounting a local defense on the spot.