#ketamine as a Bridge Therapy: Reducing Acute #suicidality in Hospital Settings (Lie, et al, 2026) “Ketamine's mechanism-of-action through mTORC1 is much faster than SSRI's downstream transcriptional regulation, leading to quicker relief of suicidal symptoms and the removal of the danger zone lag period. The current literature suggests that a controlled, supervised subanesthetic dose of Ketamine in a clinical setting has low risks of addiction or abuse…” https://pubmed.ncbi.nlm.nih.gov/41827588/ #mentalhealth

Ketamine as a Bridge Therapy: Reducing Acute Suicidality in Hospital Settings - PubMed
This narrative literature review explores the clinical use of Ketamine as part of an untested hypothetical model framework for bridge therapy for acute suicidality. Long-term suicide rates continue to increase in the United States and in many other countries, creating a pressing public health challe …