On descending control of thoracic GABAergic neurons that presynaptically (i.e., axo-axonically) modulate leg proprioprioceptive axons. So cool to see Wolf and Burrows 1995 in locust revisited in fruit flies:

"Selective presynaptic inhibition of leg proprioception in behaving Drosophila", Dallmann et al (Tuthill lab @tuthill ) 2025
https://www.nature.com/articles/s41586-025-09554-2

#neuroscience #Drosophila #proprioception #connectomics

Selective presynaptic inhibition of leg proprioception in behaving Drosophila - Nature

A study in Drosophila has identified a neural circuit that selectively suppress movement-encoding proprioceptors during self-generated movements such as walking and grooming.

Nature