I wasn't thinking about this too much during the last few years, but ever since I was having a look at @kagihq 's #OrionBrowser I started to realize how truely amazing @mipstian 's #Wipr is. Give it a go if you are on Safari and you don't like ads or pop-ups. It just works out of the box! I have yet to find (chrome based) plugins that have the same effect for me on Orion. I assume uBlock would get me ~90% there, but it didn't take long for me to run into issues with a website during testing.
Really makes we want to stick with #Safari . #Orionbrowser is really well integrated into macOS and I wanted (need to) find a browser with good vertical tabs to not get lost all the time. Sadly I don't think Safari has a good solution here (tab groups don't feel like they were meant to be used like this?) and plugins don't have access to tabs I think ...