Using a forebrain assembloid model, Kim & team unveil that gene-regulating crosstalk between neurons & glial cells potentially contributes to developing schizophrenia. #preprint
#preLight prepared by Justine Gromaire, Aimee Xinxo & Jeremie Van Prooijen ⬇️ 👀 #uMontreal
Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids - preLights
Kim & team devise a forebrain assembloid model of schizophrenia to investigate the disease's complex etiology. Their model unveils that gene-regulating crosstalk between neurons and glial cells potentially contributes to developing schizophrenia.