James and Selena's paper is out in JCB!

We present a structural model of the interaction between TACC3 and ch-TOG. Then we discover Affimers that can inhibit this interaction. Expression of the Affimers in cells uncovered a new role for TACC3-ch-TOG in maintaining the pericentriolar material during mitosis.

https://doi.org/10.1083/jcb.202407002

#CellBiology #StructBio #cytoskeleton