Alexander WeberNov 29, 2024
🚨 NEW PAPER OUT IN #cerebralcortex🚨
#hurst exponent of fMRI data from the developing #humanconnectomeproject
👶
Surprisingly, at preterm age, signals were anti-correlated (H < 0.5) but later became long-term positively autocorrelated (H > 0.5) at term; like we see in adults
https://doi.org/10.1093/cercor/bhae426
🧵
Temporal complexity of the BOLD-signal in preterm versus term infants

Abstract. Preterm birth causes alterations in structural and functional cerebral development that are not fully understood. Here, we investigate whether ba

OUP Academic
Show threadAlexander WeberNov 29, 2024
We interpret this development of the #hurst value going from anti-correlated to positively auto-correlated as being the beginning of the #brain becoming #critical like we see in the #criticalbrain
hypothesis (https://en.wikipedia.org/wiki/Critical_brain_hypothesis)
Critical brain hypothesis - Wikipedia

Show threadAlexander WeberNov 29, 2024
We also found:
- that different resting state networks had different #hurst values, and that they all increased with age
- that sensory/motor networks increased the most, while the cerebellum, midbrain, and higher-order networks developed the slowest
Show threadAlexander Weber

Perhaps most importantly, we found that the earlier you are born, the lower your #hurst value will be when compared to another baby (age-adjusted)

So at term age, healthy term-born babies had higher #hurst values than their preterm peers when measured at term-equivalent age

Nov 29, 2024 at 5:38pmWeb
Show threadAlexander WeberNov 29, 2024

Finally, the increase in #hurst was moderately correlated with indirect measures of white matter growth, suggesting a link

#neonates #neuroscience #neuroimaging