'The leading perceived cause of irreproducibility was a “pressure to publish”...'
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https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002870

Biomedical researchers’ perspectives on the reproducibility of research

There is growing interest in the reproducibility of research and ways to enhance transparency. This study uses an international survey of more than 1900 biomedical researchers to reveal the perceived causes of irreproducibility of research results, experience of conducting replication studies, and knowledge of relevant funding and training.