enmodo ⚛️ 🧬 🇺🇦 🍉

Mice studies suggest that gut microbiome friendly oat and barley fiber containing beta-glucan can increase butyrate in the gut. "Butyrate induces the release of glucagon-like peptide-1 (GLP-1), which is the natural protein that synthetic drugs like Ozempic mimic to stimulate insulin release." This lead to weight loss in the mice.

The research has not been replicated on humans yet but you can readily buy beta-glucan and butyrate suppliments.

https://www.sciencealert.com/one-type-of-fiber-may-have-weight-loss-benefits-similar-to-ozempic

#ozempic #weightloss

One Type of Fiber May Have Weight Loss Benefits Similar to Ozempic

Research on the gut microbiome has triggered a 'revolution' in nutritional science, and in the last few years, dietary fiber has become the "new protein" – added to foods in abundance to feed our gut and boost our health.

ScienceAlert
Oct 25, 2024 at 9:48pmWeb
Show threadenmodo ⚛️ 🧬 🇺🇦 🍉Oct 25, 2024

While unreplicated studies are a dime-a-dozen imagine the impact on big pharma if it turned out that eating oatmeal or barley fiber every day was an end-run around the ludicrously high cost of GLP-1 treatments in the US. Muesli anyone?

Checking butyrate I found this paper about it's effect on obesity:

https://www.sciencedirect.com/science/article/pii/S216183132200833X

It concludes "The effect of endogenous butyrate on the gut-brain axis warrants further investigations."

I'm curious to see where this goes!

#butyrate #glp1 #BetaGlucan

Butyrate: A Double-Edged Sword for Health?

Butyrate, a four-carbon short-chain fatty acid, is produced through microbial fermentation of dietary fibers in the lower intestinal tract. Endogenous…