Could addressing metabolic health be the key to managing ALS? Recent studies link metabolic syndrome (MetS) with a higher ALS risk, suggesting that how our bodies process energy might be crucial in this devastating disease.
https://pubmed.ncbi.nlm.nih.gov/38934512/
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Metabolic Syndrome and Risk of Amyotrophic Lateral Sclerosis: Insights from a Large-Scale Prospective Study - PubMed
MetS exhibits a robust association with an increased susceptibility to ALS, particularly in individuals with a lower BMI. Furthermore, metabolites and metabolomics, as potential mediators, provide invaluable insights into the intricate biological mechanisms. ANN NEUROL 2024.