I am pretty excited about the RP2350. It addresses pretty much all my minor complaints about the RP2040 and improves on it in a number of ways. It manages to be much more powerful, yet keeps the clean and straightforward design that's so foreign to so many ARM MCUs these days.
A pair of 150MHz CM33Fs with 520KB SRAM and up to 16MB of QSPI SRAM and 16MB of XIP QSPI flash opens up a lot of possibilities, while avoiding the complexity of larger SoCs.