Comprehensive #Molecular #Epidemiology of #Influenza Viruses in #Brazil: Insights from a Nationwide Analysis, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.07.04.602044v1

For #H1N1pdm09, 2022 consensus of 5a.2a.1 & #vaccine strain A/Victoria/2570/2019 had 14 amino acid #substitutions. Key residues such as H180, D187, K219, R223, E224, & T133 are involved in hydrogen interactions with #sialic acids, while N130, K142, and D222 may influence distance interactions based on docking analyses.