A different origami-guide: Irreversible folds in morphogenesis πŸ”°

Teodora Piskova #RWTH covers work from the #MechgenLab

β€œβ€¦this #preprint seeks to explain how certain material behaviors of tissues matter for fundamental processes such as #morphogenesis…”

#preLight πŸ‘‰ https://prelights.biologists.com/highlights/elasto-plastic-transition-in-epithelial-folding-v2/

#biomechanics #development #epithelium #mechanobiology #mechanosensing

Elasto-Plastic Transition in Epithelial Folding - preLights

A different origami-guide: Irreversible folds in morphogenesis

preLights

@preLights Interesting. It'd be worth investigating what level of phenomenology we put under the word "(ir)reversible" in this context.

We'd come with a variant for that together with Matteo Rauzi: erasing #Myosin accumulation cancels the furrowing, and as Myosin reaccumulates it starts over.

#Drosophila #morphogenesis #biomechanics #gastrulation

@preLights
And we also had a variant of your pathway C of #epithelial fold formation : folding by *tensile* mechanical #buckling

(Note: these are my hands on the photo, so technically this is my own's only and single published experiment!)

#epithelium