It took five decades from the 1970s for the FDA to finally admit last year that oral phenylephrine, used as a decongestant in Sudafed and Lemsip, doesn't actually do anything.

https://www.scientificamerican.com/article/how-two-pharmacists-figured-out-that-decongestants-dont-work/

#ColdAndFlu #Phenylephrine #FDA #Decongestants #Lemsip #Sudafed #ClinicalPharmacology

How Two Pharmacists Figured Out That Decongestants Don’t Work

A loophole in FDA processes means older drugs such as those in oral decongestants weren’t properly tested. Here’s how we learned the most popular one doesn’t work

Scientific American