Kriszta Satori

At last some good news:
Scientists hail new #antibiotic that can kill drug-resistant bacteria

#Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trials
https://www.theguardian.com/science/2024/jan/03/scientists-new-class-antibiotic-kill-drug-resistant-bacteria?CMP=Share_AndroidApp_Other

Scientists hail new antibiotic that can kill drug-resistant bacteria

Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trials

The Guardian
Jan 3, 2024 at 10:23pmWeb
Show threadIceNineJan 3, 2024

@fulelo

Will be interesting to see how this AB tracks - including whether resistance pops up rapidly if it can pass trials, and whether P. aeruginosa is also affected.

Show threadOzzie D, NP-hard  Jan 4, 2024
@IceNine @fulelo This peptide has been tweaked to target a lipid-transport mechanism specific to Acinetobacter baumannii. It won't work on other species. Which is not necessarily bad -- broader-spectrum antibiotics are harder on the host microbiome.
Show threadIceNineJan 4, 2024

@ozdreaming @fulelo

Cheers, am on leave atm, so haven't looked i to further - guessing that possibilities of other target species, as hinted at, would be via further tweaking?