Bernhard Schermer📣 Thrilled to share: Lioba and Inês' study on NUPs and the 🦛 effectors YAP/TAZ is now live at HMG - adding another puzzle piece to the role of YAP/TAZ in FSGS.
Congrats and a huge THANKS to the entire team for the fantastic work. 🙌🔬
https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddad135/7241341?utm_source=advanceaccess&utm_campaign=hmg&utm_medium=email
#Research #Science #Podocyte #FSGS #RareDisease #Kidney #Nephrology #Genetics #openaccess
The role of the FSGS disease gene product and nuclear pore protein NUP205 in regulating nuclear localization and activity of transcriptional regulators YAP and TAZ
Abstract. Mutations in genes encoding nuclear pore proteins (NUPs) lead to the development of steroid-resistant nephrotic syndrome (SRNS) and focal segmental gl