Psychiatry needs more simulations: the case of serum lithium concentrations

https://awaisaftab.substack.com/p/psychiatry-needs-more-simulations

Psychiatry needs more simulations: the case of serum lithium concentrations

Guest post by the physicist Alex Mendelsohn

Psychiatry at the Margins

@awaisaftab

Very interesting - thanks for posting.

A bit OT, but would like to mention that Li is toxic at typical doses in ppl w/ multiple system atrophy.

So far I've not come across an explanation, but study of Li toxicity in MSA might lead to a better understanding of disease mechanisms. I suspect there might be a connection with glycine & heme.

https://doi.org/10.1007/s00415-012-6655-7
https://doi.org/10.1177/1049909111434633

#MultipleSystemAtrophy #lithium