A commentary by @[email protected], Yaquelin Ortiz-Miranda and @[email protected] -- on @[email protected] 𝑩𝒂𝒆𝒍 𝒆𝒕 𝒂𝒍.'s study, both just out @[email protected].
📃https://go.nature.com/3uxhxEm
@[email protected] @[email protected] @[email protected]
🐦🔗: https://twitter.com/OncoUNILCHUV/status/1600422261869379584
IL-2 engineered MSCs rescue T cells in tumours - Nature Cell Biology
IL-2 is a powerful growth factor for T cells. New work shows that immune checkpoint blockade depends upon the presence of IL-2, and that mesenchymal stem cells can be efficiently engineered to safely deliver it directly in advanced tumours to rescue CD8+ T cell responsiveness to anti-PD-L1 antibody treatment.