RT @yaneerbaryam@twitter.com
New study: Men infected with COVID have one third less sperm compared to uninfected men over 3 months later. Of 100 men infected and not hospitalized four had no viable sperm. Of 100 men not infected, none had this condition.
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https://onlinelibrary.wiley.com/doi/10.1002/jmv.27971
🐦🔗: https://twitter.com/yaneerbaryam/status/1596922071786741760
Some Long Covid symptoms, e.g., alcohol intolerance, could be due to lowered activity of aldehyde dehydrogenase, particularly ALDH2. I submitted a related hypothesis to the Patient-Led Hypothesis Generation Panel which provides background & refs (1).
Inhibition of aldehyde dehydrogenase causes lower sperm count & has been investigated as a means of male birth control (2).
1- https://docs.google.com/document/d/1XBe3xkZLUtcTUZjd07nH97jjL9QR5Vt3YS08zo7WpOY/edit?usp=sharing
2- https://www.bloomberg.com/news/features/2017-08-03/why-we-can-t-have-the-male-pill
Hypothesis: Increasing the activity of aldehyde dehydrogenase 2 [ALDH2] could reduce markers of lipid peroxidation and improve symptoms of Long Covid. Rhyothemis princeps 31 October 2022 Al-Hakeim et al. [1] report increased markers of nitrosative stress and lipid peroxidation, including eleva...
Jaclyn Ferreira
Rhyothemis