Aurelien DugourdNov 9, 2022

Hi everyone, I will be teaching how to integrate #multiomics data with prior knowledge #networks at EBI #multiomics course: https://www.ebi.ac.uk/training/events/introduction-multiomics-data-integration-and-visualisation-2/

I will mainly focus on the cosmosR tool, which allows to find mechanistic hypotheses between signalling and metabolism. You can learn more by checking our publication: https://www.embopress.org/doi/full/10.15252/msb.20209730 and our github: https://github.com/saezlab/cosmosR

Introduction to multiomics data integration and visualisation -

Introduction to multiomics data integration and visualisation -

Show threadMarc Chevrette
@dugourdAjf does it have to be human?
Nov 9, 2022 at 1:16pmWeb
Show threadAurelien DugourdNov 9, 2022

@wildtypeMC technically yes, but our plans to roll out cosmos networks for other organisms will rely mainly on homology.

That means that at this point, if you have mouse or rat RNAseq/proteomic and metabolomic, you can easily convert gene IDs from mouse to human and run cosmos assuming that the human prior knowledge network of signalling and metabolic reactions is similar enough to the mouse one to yield relevant mechanistic hypotheses.