BenjaminHimesBaited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias https://doi.org/10.7554/eLife.90486.3
I have many feelings about this work - feelings about ownership, openness and power dynamics in Academic labs.
They aren’t very positive feelings, but the work itself is still good, so here’s one in the “new” @eLife
#CryoEM #VisualProteomics #drugs #Pharma #academia #simulation
*edited to ad a graphic and a hashtag
Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias
2D template matching enables a streamlined single-particle cryogenic electron microscopy workflow that can be used to discover new high-resolution structural features in molecules and complexes, such as bound ligands and drugs.
Sven Klumpe