[ Blog ] Is the VMware #VCF 9 upgrade worth the cost and complexity?

With the release of VMware VCF 9, many organizations are now facing a key question: "Is the VMware VCF 9 upgrade worth the cost and complexity?"

VMware Cloud Foundation (VCF) 9 appears to be a significant strategic decision with a number of potential benefits, especially for organizations http://rviv.ly/HfSzFp #aggiornamento #virtualization

[ Blog ] Is the VMware #VCF 9 upgrade worth the cost and complexity?

With the release of VMware VCF 9, many organizations are now facing a key question: "Is the VMware VCF 9 upgrade worth the cost and complexity?"

VMware Cloud Foundation (VCF) 9 appears to be a significant strategic decision with a number of potential benefits, especially for organizations http://rviv.ly/HfSzFp #aggiornamento #virtualization

Ath Bilbao favored to edge Valencia in a tight La Liga clash; kickoff at 16:15 CEST.

Athletic Bilbao 54.2%
Draw 27.3%
FC Valencia 18.6%

#Football #Soccer #LaLiga #ATH #VCF #ATHVCF

"Empirically determined baseline masking strategies and other considerations for gene-level burden tests"

https://www.nature.com/articles/s41588-026-02597-9

#bioinformatics #burden #vcf

Empirically determined baseline masking strategies and other considerations for gene-level burden tests - Nature Genetics

Systematic comparisons of different masking approaches for rare variant association tests across 54 traits in UK Biobank highlight strategies for gene-level burden analyses that increase study power and replicability.

Nature

https://primateai3d.basespace.illumina.com/

PrimateAI scores measures the pathogenicity of protein coding missense variants. When the score is close to one, it means the variant is highly likely deleterious; whereas when it is close to 0, it is generally considered benign. It is recommended to use PrimateAI score cutoff of 0.8 to distinguish benign variants from deleterious variants.

#illumina #bioinformatics #variant #vcf #score

PrimateAI-3D

PrimateAI-3D algorithm is a semi-supervised 3D-convolutional neural network for variant pathogenicity prediction, trained on 4.5 million common missense variants with likely benign consequence and precise protein 3D structures. It also leveraged language models of protein sequences and variational autoencoder on multiple sequence alignments.

Something I dropped a few times while stopping by the Vintage Computer Festival in Tukwila (Seattle) is the line

"These are compys that won't hurt you"

Sure there's lots of nostalgia action going on but there are also people who are way too young to remember any of this shit, right? But they're into it I think because

they're computers

which will NOT

hurt you

by stealing your work, reporting what you do, trying to make you do things

they just sit there and blink a cursor and draw pics and basically do what you tell them to do. it might not be what you _actually_ wanted, but it'll be what you told it to do and if it goes off well that's your fault...

...and not the fault of fascists who built it to fuck you up.

#vcf #vcfpnw #seattle

Siguiendo con los recuerdos del #VintageacomputerFestival de la semana pasada en Bahía Blanca. Me dio mucho gusto encontrarme con la mesa de la #RevistaReplay Aproveché de ponerme al día y comprar el número 3 que estuvo agotado y lo reeditaron. Investigación de primera sobre videojuegos 8 y 16 bit, con profundidad y humor. Llevan muchos años como la única en su tipo que se imprime en papel. https://revistareplay.com.ar/ #VCF #VCFLatam #8bit #16bit #videojuegos #videogames

--- Geheimprojekt
--- Pssssst
--- NICHT weitersagen!

Eine Überraschung für die Aussteller auf dem #VCFe

#VCF #VCFe26

Heard many great stories, talked to some very cool people and saw some great machines at the Vintage Computer Festival today. If you are in the Pacific Northwest, don't miss this!

#vcf #vcfpnw #seattle

yep, fedi's here all right #VCF #VCFPNW