Organic #molecules delivered from #extraterrestrial materials may have played a key role in supplying building blocks for #life on #Earth.

Now scientists report all five canonical #nucleobases—purines (#adenine and #guanine) and pyrimidines (#cytosine, #thymine and #uracil)—in samples returned from the C-type #asteroid (162173) #Ryugu.

Samples from Ryugu, #Bennu and #Orgueil, which have a similar mineralogy and elemental composition, show purine-to-pyrimidine ratios negatively correlating with #ammonia.

These observations indicate that the nucleobases in these samples may have formed via a shared pathway depending on the physicochemical environment of the respective parent bodies.

The detection of diverse nucleobases in asteroid and meteorite materials demonstrates their widespread presence throughout the Solar System and reinforces the hypothesis that carbonaceous asteroids contributed to the #prebiotic chemical inventory of early Earth.

#astronomy #astrobiology
https://www.nature.com/articles/s41550-026-02791-z

A complete set of canonical nucleobases in the carbonaceous asteroid (162173) Ryugu - Nature Astronomy

Samples returned from the asteroid Ryugu contain all five canonical nucleobases (A, G, C, T and U). Their presence in Ryugu and Bennu supports the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth.

Nature

❛❛ #adenine #guanine #cytosine #thymine & #uracil … necessary to build #DNA & #RNA … traces of important organic compounds like xanthine, hypoxanthine, & nicotinic acid (#vitamin B3).
In addition to suggesting that life could exist elsewhere in the #universe, the #molecules found on Bennu raise provocative questions about the #origins of #life on #Earth. ❜❜

#Bennu #asteroid was discovered in 1999 & sampled in 2020.

🔗 https://www.Salon.com/2025/01/30/building-blocks-of-life-discovered-on-asteroid-bennu/ 2025 Jan 30
🔗 https://Wikipedia.org/wiki/101955_Bennu

#Kronodon

Building blocks of life discovered on asteroid Bennu

The findings support theories that our evolution occurred thanks to space rocks colliding with our planet

Salon.com

The Basics of Purines and Pyrimidines: Understanding the Building Blocks of DNA and RNA

#Adenine, #CellSignaling, #Cytosine, #DNA, #EnzymeRegulation, #Guanine, #Purines, #Pyrimidines, #RNA, #Thymine, #Uracil #Genetics In the realm of molecular biology, few molecules are as crucial as purines and pyrimidines. These organic compounds serve as…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/15/the-basics-of-purines-and-pyrimidines-understanding-the-building-blocks-of-dna-and-rna/

The Basics of Purines and Pyrimidines: Understanding the Building Blocks of DNA and RNA

#Adenine, #CellSignaling, #Cytosine, #DNA, #EnzymeRegulation, #Guanine, #Purines, #Pyrimidines, #RNA, #Thymine, #Uracil #Genetics In the realm of molecular biology, few molecules are as crucial as …

Medical Microbiology & RDT Labs

Deciphering the Blueprint of Life: Exploring the Structure of DNA

#Adenine, #Blueprint, #Cytosine, #DeoxyriboseSugar, #DNA, #DNACoiling, #DoubleHelix, #Guanine, #Histone, #MajorGroove, #MinorGroove, #NitrogenousBases, #Nucleotide, #Phosphate, #StructureOfDNA, #Thymine, #WatsonAndCrick #Biochemistry, #Genetics The discovery of the structure of DNA stands as one of the most significant milestones in the history of science. Deoxyribonucleic acid, or DNA, is the molecule…

https://micrordt.wordpress.com/2024/04/27/deciphering-the-blueprint-of-life-exploring-the-structure-of-dna/

Deciphering the Blueprint of Life: Exploring the Structure of DNA

#Adenine, #Blueprint, #Cytosine, #DeoxyriboseSugar, #DNA, #DNACoiling, #DoubleHelix, #Guanine, #Histone, #MajorGroove, #MinorGroove, #NitrogenousBases, #Nucleotide, #Phosphate, #StructureOfDNA, #Th…

Medical Microbiology & RDT Labs
DNA Base Models

So to carry on with my project to build molecular models. I have built the 4 main base molecules associated with DNA dna structure infographic So t...

Paignton Library STEM Group
Structural and biochemical basis of methylmalonate semialdehyde dehydrogenase ALDH6A1

ALDH6A1, a member of the ALDH family, plays a crucial role in the catabolic pathways of valine and thymine. Dysregulation of ALDH6A1 expression has been linked to a variety of diseases. Methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency), an autosomal recessive disorder, arises from mutations in the ALDH6A1 gene. Additionally, ALDH6A1 has emerged as a biomarker for several types of severe cancer. Despite its significance, the structural and biochemical mechanisms of ALDH6A1 remain poorly explored.

Phys.org
Genome Comparison

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