A DIABETES DRUG JUST REVERSED CHROMOSOMAL AGING

As a medical school professor, I teach that telomeres -- the protective caps on your chromosomes -- only shorten with age. A new clinical trial just proved that wrong.

Researchers gave 142 people with type 2 diabetes an SGLT2 inhibitor (henagliflozin) or placebo for 26 weeks. Results:

- 90.5% of the drug group had LONGER telomeres vs. 65.6% on placebo
- Immune k... https://medicalxpress.com/news/2025-09-popular-diabetes-drug-anti-aging.html

#Telomeres #SGLT2 #MetabolicHealth #Longevity #AntiAging

Five years in and still getting younger - Chris Williamson and Bryan Johnson

#telomeres #longevity #aging

Original timestamp: 01:18:59

Harvard study of 1K people who came to their center in Boston for testing found a 75% reduction in loss of telomere length over 4 years from 2K IU of vit D3 daily. Given Boston, likely these people were mostly vit D deficient to begin with. I'm not finding the free full text of the study, only articles about it like [1], and the study abstract [2].

[1] https://www.ifm.org/articles/vitamin-d-slow-telomere-shortening

[2] https://doi.org/10.1016/j.ajcnut.2025.05.003

#vitaminD #telomeres

“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #Harvard #geneadons #dna #VITAL #vitaminD #telomeres #epigenetics https://news.harvard.edu/gazette/story/2025/05/vitamin-d-supplements-may-slow-biological-aging/
Vitamin D supplements may slow biological aging

Trial shows protection against telomere shortening, which heightens disease risk.

Harvard Gazette
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Vitamin D may do more than boost immunity — it could help slow cellular aging. Groundbreaking findings from a major trial. #HealthyAging #VitaminD #Telomeres

https://geekoo.news/vitamin-d-and-the-aging-clock-a-new-role-in-cellular-longevity/

Bacterial 'jumping genes' can target and control chromosome ends

Transposons, or "jumping genes"—DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of antibiotic resistance.

🔬 Call for abstracts – deadline is 18 March ✨

The EMBO | EMBL Symposium 'The ageing genome: from mechanisms to disease' is back with a fresh international speaker lineup! 🧬

#EESAgeing will bring together experts in chromosome biology, ageing sciences, and disease research.

Don't miss your chance to present! Submit your abstract here: https://s.embl.org/ees25-05-ma

#ageing #DNArepair #genomestability #emblevents #telomeres #DNAdamageresponse #ageinggenome #chromatinstability #epigenetics

The ageing genome: from mechanisms to disease

Data-driven techniques enhance understanding of cell division

Research from Umeå University paves the way for a quantitative data analysis method to study the cell division process in individual cells. The improved resolution will promote advanced cell analysis in the human body, especially in cases of incorrect cell division such as in the context of cancer. The research is published in Nucleic Acids Research.

Phys.org