Nicole SharpDec 17

Marangoni Bursting With Surfactants

A few years ago, researchers described how an alcohol-water droplet atop an oil bath could pull itself apart through surface tension forces. Dubbed Marangoni bursting, this phenomena has shown up several times since. Here, researchers explore a twist on the behavior by adding surfactants to see how they affect the bursting phenomenon. (Video and image credit: K. Wu and H. Stone; via GFM)

#flowVisualization #fluidDynamics #instability #MarangoniBursting #physics #science #surfaceTension #surfactant

Nicole SharpOct 3, 2024

When a drop settles gently against a pool of the same liquid, it will coalesce. The process is not always a complete one, though; sometimes a smaller droplet breaks away and remains behind (to eventually do its own settling and coalescence). When this happens, it’s known as partial coalescence.

Here, researchers investigate ways to tune partial coalescence, specifically to produce more than a single droplet. To do so, they add surfactants to the oil layer surrounding their water droplet. The surfactants make the rebounding column of water skinnier, which triggers the Rayleigh-Plateau instability that’s necessary to break the column into more than one droplet. (Image and video credit: T. Dong and P. Angeli)

https://fyfluiddynamics.com/2024/10/tweaking-coalescence/

#2022gofm #coalescence #coalescenceCascade #fluidDynamics #instability #physics #PlateauRayleighInstability #science #surfaceTension #surfactant

Ms. Que BanhSep 7, 2024

Telling my friend about DOC #surfactant in creek. He was worried at first sight but it's not pollution. It is a #natural occurrence. It's an essential part of a healthy & functioning #forest #ecosystem.

Naturally occurring stream foam can be off-white, light tan, or brown. Formed by dissolved organic matter/dissolved #organic carbon (DOC). DOC results from the breakdown of organic debris, tannins & #watershed soils rich in organic materials.

#creek #water #nature #Educational #Wsanec #HighlandsBC #Saanich #YYJ #NatureVideo #NatureNerd #VictoriaBC #VancouverIsland #PacificNorthwest #VanIsle #PNW #Cascadia #NiftyNature #ecological #environment

99nicuAug 24, 2024
New EBNEO commentary, about surfactant through LMA (Laryngeal Mask Airway).
Check out and join the discussion here in our forums -> https://99nicu.org/forums/topic/2717-ebneo-commentary-surfactant-administration-via-laryngeal-mask-airway-versus-brief-tracheal-intubation-in-preterm-infants/
#NICU #surfactant #NeoMastodon #nicuverse
EBNEO COMMENTARY: SURFACTANT ADMINISTRATION VIA LARYNGEAL MASK AIRWAY VERSUS BRIEF TRACHEAL INTUBATION IN PRETERM INFANTS.

Mary Eileen Foster and Harsha Gowda from Neonatal Unit, Birmingham Heartlands Hospital, UK, write an EbNeo Review on: Gallup JA, Ndakor SM, Pezzano C, Pinheiro JMB. Randomized Trial of Surfactant Therapy via Laryngeal Mask Airway Versus Brief Tracheal Intubation in Neonates Born Preterm. J Pediat...

99NICU
Giuseppe MichieliJul 23, 2024

A #therapy for suppressing canonical & noncanonical #SARS-CoV-2 viral #entry & an intrinsic intrapulmonary #inflammatory response, Proc Natl Acad Sci USA: https://www.pnas.org/doi/abs/10.1073/pnas.2408109121?af=R

We have harnessed our patient-specific, induced pluripotent stem cell–derived, multicell #lung #organoid model to investigate critical aspects of #COVID19, including viral tropism & routes of entry, lung-specific immune response, & a role for #surfactant protein B in innate immunity...

Stefan Johansson, MD PhDJan 5, 2024
While updating our local RDS guideline and #surfactant treatment, I am looking into the data about the dose increase from 100 to 200mg/kg of poractant. While this higher dose is in the Eu consensus paper fr 2022, it seems the actual data about this is pretty vague and less convincing. Anyone else sharing the same impression about this literature? #NeoMastodon
Matt WillemsenDec 28, 2023
The science of the ideal salad dressing
https://theconversation.com/the-science-of-the-ideal-salad-dressing-216159 #SaladDressing #mixture #composition #FoodScience #emulsions #surfactant
The science of the ideal salad dressing

There is a large energy cost to breaking apart and mixing the water and oil layers. The secret to blending them is to add an extra ingredient known as a ‘surfactant’ or emulsifier, like mustard.

The Conversation
The Incubator PodcastDec 11, 2023
🫁 An interesting meta-analysis published in ADC F&N showing that while additional #surfactant doses after 48hrs of life may not reduce the incidence of death/BPD, it did reduce the need for post-discharge respiratory support. Check out episode #167 of the podcast for more on the latest research published in #neonatology. #nicu #neonatal #babies #BPD #innovation https://fn.bmj.com/content/early/2023/11/23/archdischild-2023-326333
Late surfactant administration after 48 hours of age in preterm neonates with respiratory insufficiency: a systematic review and meta-analysis

Objective To systematically review and meta-analyse the effect of late surfactant administration versus placebo in reducing the incidence of death or bronchopulmonary dysplasia (BPD) in preterm infants. Design PubMed, EMBASE, CINAHL and Cochrane CENTRAL were searched until 30 May 2023, for randomised controlled trials (RCTs) comparing administration of surfactant after 48 hours of age versus placebo in preterm ventilator-dependent neonates. The primary outcome was incidence of death or BPD at 36 weeks’ postmenstrual age (PMA). Secondary outcomes included incidence of BPD at 36 weeks PMA, pre-discharge mortality, use of postnatal steroids, post-discharge respiratory support, treatment with steroids or hospitalisation prior to 1-year corrected age. Results Pooled analyses of four RCTs (N=850) showed no statistically significant difference between groups in the incidence of death or BPD at 36 weeks’ PMA (relative risk (RR) 0.99; 95% CI 0.90 to 1.10; Grades of Recommendation, Assessment, Development and Evaluation (GRADE): moderate). Late surfactant administration significantly decreased the need for post-discharge respiratory support prior to 1-year corrected age (two RCTs; N=522; RR 0.72; 95% CI 0.59 to 0.89; GRADE: low). Other secondary outcomes did not differ significantly between the groups. Conclusions Administration of late surfactant does not improve the rates of death or BPD at 36 weeks when administered to preterm infants with prolonged respiratory insufficiency. Additional adequately powered trials are needed to establish the efficacy of late surfactant therapy in preterm infants. PROSPERO registration number CRD42023432463. Data are available upon reasonable request.

ADC Fetal & Neonatal Edition
Brian HamptonJan 10, 2023

I use the #surfactant #SDC extensively for #proteomics sample prep. It is compatible with #Trypsin and easily removed. Very occasionally the solution will gel - and I can reverse this fortunately. Today I discovered why this happens:

https://doi.org/10.1021/jp409626s
"The results demonstrate that the gels are formed by intertwined fibrils, which are induced by enormous cycles of NaDC molecules driven by comprehensive noncovalent interactions, especially the hydrogen bonds."

Ruud VeldhuizenDec 19, 2022
Here is link to the lay summary of our recent publication #vaping #surfactant
https://link.growkudos.com/1lv0jwdigao
The negative effect of vaping on the material that stabilizes your lung, surfactant.

Whereas vaping was initially as a smoking cessation tool, many people that vape have never smoked. This is especially true for teenagers and young adults. many of which take up vaping because of the variety of appealing flavours. Unfortunately, we don't know what impact vaping has on lung health.