Show threadRhyothemis1d ago

more on immunological effects of sucralose:

Artificial sweetener sucralose: a possible modulator of autoimmune diseases [2023]
https://doi.org/10.1038/s41392-023-01607-0

#immunology #sucralose #autoimmunity #ArtificialSweeteners

Rhyothemis2d ago

Artificial sweetener may interfere with immunotherapy | Damon Runyon Cancer Research Foundation
17 Dec 2025
https://www.damonrunyon.org/discovery/artificial-sweetener-may-interfere-immunotherapy

#cancer #immunology #sucralose

Artificial sweetener may interfere with immunotherapy | New Discoveries

New research from Damon Runyon-Dale F. Frey Breakthrough Scientist Abigail E. Overacre-Delgoffe, PhD, and her lab at the University of Pittsburgh suggests that sucralose—the sugar substitute found in many “sugar-free” sodas, yogurts, and snack foods—may interfere with cancer immunotherapy. Their findings indicate that the widely used artificial sweetener changes the composition of the gut microbiome in ways that weaken patients’ immune systems and blunt the effectiveness of immune checkpoint inhibitors, a class of drugs that unleash T cells to attack tumors.

skuaMay 20

Food packaging and labeling

So thrilled to find that the apparently nice looking carbonated drink below does not just have lemon, lime and bitters, fruit juice and natural flavours (& no added sugar) in it.

It contains also:
Variously; artificial sweeteners, intense sweeteners, sugar substitutes.
There are indications that these things change the human microbiome.
With unknown outcomes.
950 - #AcesulfamePotassium
952 - #Cyclamate
955 - #Sucralose

scinexx - das wissensmagazinApr 22
Süßstoffe: Negative Effekte bis in die nächste Generation? Stevia und Sucralose verändern Darmflora und Genaktivität bei Mäusen und ihren Nachkommen. #Suessstoff #Stevia #Sucralose #Süßstoff #Zuckerersatz
https://www.scinexx.de/news/medizin/suessstoffe-negative-effekte-bis-in-die-naechste-generation/
Süßstoffe: Negative Effekte bis in die nächste Generation?

Nicht nur positiv: Süßstoffe gelten als gesunde Alternative zu Zucker – aber auch sie sind nicht unproblematisch. Jetzt legt eine Studie mit Mäusen nahe,

scinexx | Das Wissensmagazin
UmWerker 🕊 ☮️ 🤘Apr 15

Wer noch Kinderwünsche hat, kann sich gar nicht genug darüber informieren, welche Gefahren im Vorfeld bestehen. Sich #Zucker reduziert zu ernähren, ist sicher gut, hat aber leider auch seine Tücken. #Stevia, aber besonders #Sucralose scheinen generationsübergreifende Folgen zu verursachen.

https://www.spektrum.de/news/veraendern-suessstoffe-den-stoffwechsel-und-die-darmflora/2319452

Süßstoffe hinterlassen Spuren über Generationen

Süßstoffe wie Sucralose und Stevia beeinflussen bei Mäusen Stoffwechsel, Darmflora und Genaktivität noch bei den Nachkommen. Ein Zuckerersatz wirkt dabei besonders stark.

Spektrum.de
skuaApr 7

Supplements
Just realised that my nice cheap vitamin C tablets are sweetened with sucralose.

And drugs com tells me, "... it is not expected to have a major effect on your health".

A single pimple wouldn't be worth getting from this stuff as I value things.
And any major health effect will be unexpected?

Oh good, and I expected all the family's "major health effects" from Covid, through cancer & Alzheimers to hemorrhagic stroke?

#Supplements #VitaminC #ArtificialSweetener #Sucralose

European Food Safety AuthorityMar 23
#Sucralose explained in plain language Our summary explains EFSA’s experts’ conclusions on sucralose — including current authorised uses and why extending its use at high temperatures could not be confirmed. Read it here: 🔗 link.europa.eu/mpMXPN #FoodSafety #FoodAdditives
hauswirtschaft_infoMar 15

Sind die Süßstoffe #Aspartam und #Sucralose krebserregend?
Dieser Frage geht Dr. Mai Thi Nguyen-Kim in ihrem Video auf dem Kanal MAITHINK X nach. Leicht nachvollziehbar erklärt sie, wie es zu dem Verdacht kam, wie die Quellen einzuordnen sind und ob man zukünftig Lebensmittel mit Süßstoffen meiden sollte.

MAITHINK X: Krebs durch Süßstoffe?
https://www.zdf.de/video/shows/mai-think-x-die-show-102/maithink-x-suessstoffe-100

Süßstoffe: Gesund oder gefährlich?

Helfen sie wirklich beim Abnehmen? Oder kurbeln Süßstoffe den Appetit an? Von Aspartam bis Xylit, Mai nimmt Zucker-Alternativen unter die Lupe.

ZDF
European Food Safety AuthorityFeb 17
New assessment on #Sucralose (E955) Our experts concluded that sucralose continues to be safe for consumers at its currently authorised uses. Experts could not confirm the safety of extending its use, especially with prolonged high temperatures. 🔗 link.europa.eu/kBXKJ3 #FoodAdditive #FoodSafety

EFSA finds sucralose safe when...
EFSA finds sucralose safe when used as currently authorised; cannot confirm safety of extending its use

EFSA’s experts concluded that the sweetener sucralose (E 955) continues to be safe for consumers for its currently authorised uses as a food additive.

European Food Safety Authority
Alexandra Beekers 🏳️‍🌈🌍Oct 18, 2025
Association Between Consumption of Low- and No-Calorie Artificial #Sweeteners and Cognitive Decline
#Aspartame #Sucralose #dementia
https://www.neurology.org/doi/10.1212/WNL.0000000000214023
Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline | Neurology

Background and ObjectivesConsumption of low- and no-calorie sweeteners (LNCSs) has been associated with adverse health outcomes. However, little is known about the association between consumption of LNCSs and cognition. The aim of this study was to ...

Neurology