NGSX News 4th June 2026

Cancer Diagnostics, Guardant Health and Grail Bio, more companies join the Spatial Biology race, more examples of cfDNA diagnostics

Rhymes with Haystack

šŸ”¬ A breakthrough for spatial biology? This ultrafast 3D imaging method enables deep whole-organ visualization faster than ever before.

šŸ”— Rapid 3D Immunolabeling and Light Sheet Microscopy for Quantitative Analysis of Intact Tissues. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0121

šŸ“š CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#Bioimaging #3DImaging #LightSheetMicroscopy #TissueBiology #Microscopy #CellBiology #SpatialBiology #Histology

New preprint! Which segmentation algorithm should you use for image-based spatial transcriptomics — and does the answer change by tissue?

Preprint: https://www.biorxiv.org/content/10.64898/2026.04.16.718947v1

#SpatialBiology #Bioinformatics #computationalbiology #OpenScience

Researchers have comprehensively mapped the microenvironment of neuroblastoma, a highly lethal pediatric cancer, discovering that the tumors utilize surrounding immune cells as "bodyguards" and specific proteins as "shields" to evade natural cell death.
#Pediatric #Oncology #MolecularBiology #SpatialBiology #sflorg
https://www.sflorg.com/2026/04/ongy04012601.html
Shields and bodyguards: scientists uncover the hidden defences of a deadly childhood cancer

Neuroblastoma accounts for approximately 10 percent of all pediatric cancer deaths

I’m pleased to announce that I’m serving as Editor in Chief of a new journal focused on #spatialbiology called EXO - Beyond the Cell. We have assembled a world-class editorial board. My deepest thanks to the outstanding scientists who have agreed to help guide EXO. no subscription fees — all papers immediately available worldwide. No author publication charges until at least 2030. (Very helpful with the new NIH policy) Rapid and concise reviews. High quality reviewers.
https://www.sciexplor.com/articles/EXO.2026.0001
EXO - Beyond the Cell, a journal about how cells interact with their environment

Rhymes with Haystack | Albert | Substack

Biotech, Next Generation Sequencing, Single cell and Spatial Biology, Next Generation Proteomics, Synthetic Biology, Small Molecules and Biologics pharma, and related topics. Click to read Rhymes with Haystack, a Substack publication with thousands of subscribers.

#M&A season in #SingleCell and #SpatialBiology Curio Bio -> Takara Scale -> 10X Genomics $TXG Fluent -> Illumina $ILMN Parse -> Qiagen $QGEN being the latest to be announced.
SPARTA — Spatial Reasoning and Therapeutics with AI : From Omics to Imaging

A few more #SingleCell and #SpatialBiology methods have been published recently, making it a total of 362 in the table I compiled over the years. lookerstudio.google.com/reporting/c3...