A specialized class of inhibitory neurons, known as
#somatostatin (SST)-expressing neurons, establishes a foundational level of
#neural inhibition in the visual
#cortex that appears to be independent of sensory experience.
#Neuroscience #DevelopmentalBiology #Neurobiology #sflorghttps://www.sflorg.com/2026/02/ns02022601.html
How a unique class of neurons may set the table for brain development
This research challenges the dogma that all brain circuit development is driven by experience and pruning
Diversity of somatostatin
#GABAergic inhibitory interneurons. Study compares anatomical & physiological properties of 2 subtypes of
#somatostatin #interneuron, finding key differences that may underlie their functionalities
#PLOSBiology https://plos.io/3wRTXXD
Synaptic and dendritic architecture of different types of hippocampal somatostatin interneurons
Somatostatin GABAergic inhibitory interneurons have important roles in neuroplasticity, learning and memory, but the functional roles of some subtypes are not well understood. Here, the authors compare the anatomical and physiological properties of two subtypes of somatostatin interneurons, finding key differences that could underlie their functionalities and providing essential information to model the hippocampal network.
New insights into how hippocampal
#MemoryFormation & recall is controlled by a disinhibition-based mechanism, supported by
#hippocampal #somatostatin interneurons & their pontine
#brainstem inputs from the
#NucleusIncertus #PLOSBiology https://plos.io/3NkleaD
Fear memory recall involves hippocampal somatostatin interneurons
This study provides new insights into how hippocampal memory formation and recall is controlled by a disinhibition-based memory mechanism, supported by hippocampal somatostatin interneurons and their pontine brainstem inputs from the nucleus incertus.
Scientific Frontline
PLOS Biology
