Mastodawn

Africa: Single-Dose Treatment for Sleeping Sickness Receives Approval: [Drugs for Neglected Diseases initiative (DNDi)] Kinshasa / Paris / Geneva / Amsterdam -- · Recommendation based on Phase II/III study demonstrating up to 96 per cent success rates at 18 months across both early and advanced stages of T.b. gambiense, the most common form of sleeping sickness· The therapy, given as a single dose of three… http://newsfeed.facilit8.network/TRC0k5 #SleepingSickness #TBDisease #PublicHealth #GlobalHealth #WHO

ChemistryViews Jan 29, 2025

Total Synthesis of Ukabamide, a Drug Candidate against Sleeping Sickness:
Lipopeptide from marine cyanobacteria could lead to new antitrypanosomal drugs
https://www.chemistryviews.org/total-synthesis-of-ukabamide-a-drug-candidate-against-sleeping-sickness/

#marinelipopeptide #sleepingsickness #antitrypanosomal #drugdevelopment #chemistry #chemistryviews #chemviews

Total Synthesis of Ukabamide, a Drug Candidate against Sleeping Sickness - ChemistryViews

Lipopeptide from marine cyanobacteria could lead to new antitrypanosomal drugs

ChemistryViews

Punk Metal n Bowie Dec 22, 2024

#Geneticmutations in #parasites may lead to #globalspread of #sleepingsickness
https://phys.org/news/2024-12-genetic-mutations-parasites-global-sickness.html

Genetic mutations in parasites may lead to global spread of sleeping sickness

Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes, a study shows.

Phys.org

Lukas VFN 🇪🇺Jul 24, 2023

The prospect of a better treatment for Chagas disease and sleeping sickness https://blogs.biomedcentral.com/bugbitten/2023/07/21/the-prospect-of-a-better-treatment-for-chagas-disease-and-human-african-sleeping-sickness/

#Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections https://www.science.org/doi/10.1126/science.adh0614

"#NeglectedTropicalDiseases caused by #SingleCelled #parasites (#trypanosomatids) include #ChagasDisease, #SleepingSickness & #leishmaniasis. Progress in treatment of these #diseases had been slow, though large chemical library screens are now showing promising results."

BugBitten The prospect of a better treatment for Chagas disease and human African sleeping sickness

Sarah Newey Nov 30, 2022

Exciting results on a new sleeping sickness drug: 95% effective in late stage patients, and 100% effective in those diagnosed early in a trial in the DRC & Guinea. Could this be the beginning of the end of the disease?

https://www.telegraph.co.uk/global-health/science-and-disease/new-cure-sleeping-sickness-could-eliminate-nightmare-disease/

Also more stunning 🦟 pics from Simon Townsley..

#neglecteddiseases #sleepingsickness #globalhealth #tsetseflies