#Plasmodium #parasites have a pair of organelles called rhoptries, made anew every replicative cycle. @davidanaguano @MuralidharanLab &co show that RON11 triggers biogenesis of the second
#rhoptry and is important for
#erythrocyte invasion
#PLOSBiology https://plos.io/3XQeiqY 
Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion
Plasmodium parasites have a pair of unique organelles called rhoptries that are made anew every replicative cycle. This study shows that the RON11 protein triggers de novo biogenesis of the second rhoptry and is important for parasite invasion of erythrocytes.
Secretion of
#rhoptry factors is essential for invasion by
#Apicomplexan #parasites. @RouaaBc @gaelle_lentini @SoldatiLabToxo &co identify
#Toxoplasma RDF3 as crucial for invasion, priming microtubule-associated vesicles for rhoptry discharge
#PLOSBiology https://plos.io/3Z4bbNx
Toxoplasma gondii rhoptry discharge factor 3 is essential for invasion and microtubule-associated vesicle biogenesis
Regulated secretion of rhoptry factors is essential for host cell invasion by Apicomplexan parasites. This study identifies the protein rhoptry discharge factor 3 (RDF3) of Toxoplasma gondii as crucial for invasion, by priming microtubule-associated vesicles for rhoptry discharge.
A conserved complex of microneme proteins mediates rhoptry discharge in #Toxoplasma:
Sebastian Lourido and coworkers show that three #apicomplexan-specific #microneme proteins form a complex essential for #rhoptry discharge and invasion
https://www.embopress.org/doi/full/10.15252/embj.2022113155
PLOS Biology
The EMBO Journal