ohh this one has the stoned virus!

#softwareArchiving #retroComputing #retroVirus

Pregnenolone promotes immune evasion through blocking endogenous #retrovirus expression.

Sexual abstinence promotes #tumor progression by inducing #pregnenolone production. Pregnenolone facilitates the formation of H3K9me3 to suppress #ERV replication.

https://www.sciencedirect.com/science/article/abs/pii/S1550413125005844 #microbiology #cancer

my features published in #CurrentBiology this year, issue 22: Looking at the fight against #AIDS / #HIV after the recent good news on #prophylactics.
https://proseandpassion.blogspot.com/2024/11/good-news.html

#science #medicine #retrovirus #publicHealth #STI

good news

It doesn't happen very often these days, but my latest feature has some very good news to report, so enjoy: Prophylactic progress again...

Humoral, innate antibodies - PAMP recognition through germline "natural" antibodies

#immunology #IgM #retrovirus

https://www.science.org/doi/10.1126/sciimmunol.add6608

For @loewe's #MusicWomenWednesday, here's a throwback to 2013 and my first time witnessing #LydiaLunch setting us all on fire with her raw, unfiltered, and cathartic energy. What a gig! 💀🔥🖤✨

https://lydialunch.bandcamp.com/track/burning-skulls-2

#BurningSkulls #Retrovirus #WeaselWalter #TimDahl #BobBert #NoWave #PostPunk #AvantGarde

Burning Skulls, by Lydia Lunch

from the album Retrovirus

Lydia Lunch
"Our lab found that an evolutionary dormant retrovirus from 6 million years ago, HML-2, a subtype of HERV-K, contributes to brain tumor formation. We demonstrated for the first time that this virus, when reactivated, plays a role in defining the stem-cell state of high-grade gliomas, promoting an aggressive form of cancer," #Cancer #Virology #Retrovirus #glioblastoma #Oncology #science https://medicalxpress.com/news/2023-07-remnants-ancient-retrovirus-aggressiveness-resilience.html
Remnants of ancient retrovirus may drive aggressiveness and resilience of malignant brain cancers

The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.

Medical Xpress
Stunningly detailed blueprint revealed of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

Phys.org
Aging in cells: reviving endogenous #retrovirus leads to #senescence ...via #innateimmunity activation. Plenty of questions spring to mind, but fascinating crossroad of #immunology and #aging
https://www.cell.com/cell/fulltext/S0092-8674(22)01530-6
@SilverGorilla2 🙏
I am not a scientist, I've read that the envelope protein of the #HERV-W #Retrovirus might be an aggravating factor in #MS and that it would also play a role in inflammatory #psychosis, as well as in min. 25% of #longcovid. All this has been published. Forseps.org has been following this trail for 10 years. A P2 trial with #temelimab targeting this protein is recruiting in 🇨🇭 Switzerland. The P2 in #MS had positive results, presented at #ECTRIMS2022#mschat