The EMBO Journal#Amyloid protein assemblies can be toxic, but are some also of use to cells?
Diana Ottoz, Luke Berchowitz et al show that assembly of yeast #RNA-binding protein #Rim4 occurs reversibly in response to nutrient stimuli and mediates its #transcriptional #repressor function
Alessandro Esposito#GeneRegulation couples transfers of #information to transfers of mass and energy (episode II). Also the lac-operon is often used as a simple example of gene reg. The lac-operon utilizes an inducible #repressor and #activator to sense the #concentration of lactose and glucose (1) and to regulate the metabolic pathway that generates glucose from lactose (2). Metabolic and information fluxes are thus coupled to give E. coli the capability of taking a #decision. ...
#GeneRegulation couples transfers of information to transfers of mass and energy. The E. coli Trp-operon is often used as a simple example of gene reg. Genetic info transfers from #DNA to #proteins, including the synthesis of (1) a #repressor gene. In absence of tryptophan, the #operon induces the synthesis of the #metabolic #enzymes for its production (2). Tryptophan then binds the repressor (3)...
