6. 7/8 🌐📚 Future prospects: there was so little biochemical data for our specific proteins, we had to rely on genome-wide data (PBMs). We could then estimate Kd for ANY sequence. That means, also for sequence variants.
Our earlier Framework Model v2 (FMv2) and FM-Life models link the clock right up, through plant metabolism, growth, development and physiology, to seed-to-seed adaptation in real weather.
Anyone who assembles these parts gets to predict how an Arabidopsis genome sequence variant will be adapted to climatic conditions. With a full causal chain. The mechanisms of evolutionary adaptation.👀 #GoForIt
Sure it’s simplified and there’s much to validate but it’s there. DNA-binding Kd is just where we started, there’s more known biochemistry to add.
Are you a graduate student or postdoc who wants to add novel developmental biology and biophysics methods to your research? Then have a look at #EMBLDevBio, where you'll learn all about highly multiplexed RNA fluorescent in situ hybridisation, quantitative imaging and analysis, machine learning based image segmentation, and more 🥼👀
📥 Apply by 26 March 2025
🔗 https://s.embl.org/ptd25-01-ma
🗺️ EMBL Heidelberg
📅 2 – 9 July 2025
Job - Alert 🚀
🎓 SEVEN PHD POSITIONS
Deadline: 2025-01-03
Location: Germany, Berlin
APPLY: https://www.academiceurope.com/job/?id=5964
#hiring #Biophysics #Epidemiology #Immunology #InfectionBiology #MedicalBiotechnology #Microbiology #Parasitology #PhD #quantitativebiology
It turns out it may be better to have (genetically) curly than straight hair (or no hair at all), 👩🏽🦱 especially under extreme heat and/or sun exposure - shows a recent study by
@TinaLasisi
et al. 🧬
Tightly curled hair came off best in their experiment than other hair types (bald head, straight hair, moderately curled hair) regarding minimising sweating and overheating.
#Anthropology #biologicalanthropology #QuantitativeBiology #ComputationalBiology
https://nationalgeographic.com/premium/article/curly-hair-evolutionary-advantage-brain-protect
Postdoc in Quantitative & Systems Biology @youklab
Quantitative biology of dormancy in yeast: how lifeless becomes alive
#ScienceJobs #job #quantitativeBiology
Worcester MA #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/university-of-massachusetts-chan-medical-school-umass-chan-27778-postdoc-in-quantitative-systems-biology/?feed_id=43344
Postdoc in Quantitative & Systems Biology @youklab
Quantitative biology of dormancy in yeast: how lifeless becomes alive
#ScienceJobs #job #quantitativeBiology
Worcester MA #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/university-of-massachusetts-chan-medical-school-umass-chan-27778-postdoc-in-quantitative-systems-biology/?feed_id=42168
Suggest a few good examples from mathematical and theoretical biology that can help to convince an uninitiated biologist that theory and mathematical models matter in Biology.
I need a few examples for a general talk to a broader audience of "experimental biologists."
#qBio #mathbio
#QuantitativeBiology
#theoreticalbiology
#ScienceMastodon
Andrew Millar
EMBL Events
Academic Europe
Erwin Schrödinger Institute
jobRxiv
Biplab Bose