Seit Wochen schlage ich mich - kochend - mit dem Thema #Purine herum (für den Liebsten) und kriege keinen echten Zugang, fühlt sich auch alles so spaßbefreit an... Jetzt versuche ich es mal mit zwei spezialisierten Kochbüchern.
(Kochbücher kaufe ich nur noch gebraucht bei Medimops, ökologisch sinnvoll und finanziell angenehm.)
Scientists uncover a multibillion-year epic written into the #chemistry_of_life.
#purine #biosynthesis #KEGG #evolution #ATP
https://phys.org/news/2024-05-scientists-uncover-multibillion-year-epic.html
The origin of life on Earth has long been a mystery that has eluded scientists. A key question is how much of the history of life on Earth is lost to time. It is quite common for a single species to "phase out" using a biochemical reaction, and if this happens across enough species, such reactions could effectively be "forgotten" by life on Earth.
"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"
Constructing a biosphere-scale model of the evolutionary history of metabolism based on >12,000 biochemical reactions, the authors show that a bottleneck in purine synthesis prevents metabolic expansion from geochemical precursors.
🔵 Gotta: cos'è, quali sono i suoi sintomi, le cure e la dieta consigliata?
👉 Leggi l’articolo: https://medicinaonline.co/2017/02/13/gotta-sintomi-cause-dieta-e-rimedi-per-la-malattia/
✅ #gotta #infiammazione #acidourico #articolazioni #dolore #purine #aminoacidi #EmilioAlessioLoiacono #MedicinaOnLine
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