Do people have an opinion about the Trip range of drinks? It would be nice to hear something that's not AI-generated.
I have tried Calm by Trip. I was sound asleep an hour later, slept all night, which is very rare for me, and woke up with a clear head.
If I understand correctly, this particular one has Magnesium instead of CBD, which works differently to #Propranolol but to a similar effect.
BBC Radio4 The Moral Maze
"Should Morality be Enforced?"
discussion contributor mentions #propranolol
a blood pressure medication that was shown to have a side-effect of reducing "implicit racial bias" in test subjects
Hey folks 👋
For those who don't already know, we're currently signed off work due to depression, anxiety, and burnout.
Our employer is supportive, but there are multiple, fundamental, ongoing issues with the organisation that no amount of individual support can resolve. We cannot go into more detail.
During the last 2 and a bit weeks, we've done a mixture of resting and doing tasks we've been meaning to do for ages, but neither had the time nor spoons to do.
We're still on 200 mg sertraline (an SSRI) daily, but we've made the switch from taking 150 mg bupropion (an NDRI) daily alongside to 40 mg atomoxetine (an sNRI, not an SNRI) daily alongside. We're slowly titrating up to the recommend 80 mg dose.
As we came off the bupropion steadily, we definitely felt it (i.e., mood; executive function; energy etc.), but the effects are levelling off as our atomoxetine dose steadily increases.
The bupropion had helped us for a while, both with our mental health and some ADHD struggles, but could only do so much. As such, we decided to make the unorthodox switch to atomoxetine.
Bupropion is an atypical NDRI and antidepressant: it boosts noradrenaline and dopamine (to a lesser extent). However, it's only prescribed off licence for ADHD, as it's not been shown to be effective. Atomoxetine, conversely, is mainly used to treat ADHD in people who do not respond well to stimulants, such as methylphenidate. It directly boosts noradrenaline and indirectly boosts dopamine in the prefrontal cortex by a decent amount.
Since we do not tolerate any stimulants well (even caffeine), atomoxetine is our best bet in terms of an ADHD med that also helps with our mental health.
Unlike bupropion, it doesn't have any major interactions with sertraline (only moderate), and we can take 40 mg propranolol tablets alongside to help keep our anxiety under control, rather than turning straight to 10 mg diazepam tablets.
So far, we're doing well with the switch, both physically and mentally, but it'll be a while before we know for sure whether this the ideal medication combination.
We are still very much in low power recovery mode, so don't expect anything much or consistent from us.
A last note to sign this off: from the above listed drugs, the only one we can currently get via the NHS is sertraline. We may be able to get atomoxetine through the NHS in the future, but that's dependent on us ever actually getting a formal ADHD diagnosis 😮💨 The waiting lists are rather long... even when using the Right To Choose a mental health service provider.
Apologies for any typos.
#MentalHealth #depression #anxiety #burnout #neurodivergent #ADHD #AuDHD #NHS #NHSEngland #sertraline #SSRI #bupropion #NDRI #atomoxetine #sNRI #serotonin #noradrenaline #dopamine #RightToChoose #propranolol #diazepam #stimulants #methylphenidate
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Propranolol did not impact social interaction measures or language, but there were indications of a beneficial effect for anxiety. This will need confirmation in a larger multicenter trial, monitoring markers or characteristics to identify those participants most likely to respond to propranolol for …
Looking for ways to fight anxiety? Check out "Conquer Anxiety with Propranolol: The Ultimate Patient's Guide 2024". Get the lowdown on the benefits & proper usage.
I also have a hunch that #CBD + #propranolol might be very useful for many types of serious #anxiety and #PTSD in particular.
Propranolol is already seeing strong early support for use in PTSD, both soon after trauma and much later; I suspect the huge improvement in my #socialanxiety over the last 10 years was in part due to propranolol and by the same mechanism proposed for its beneficial effect in PTSD. I suspect that CBD and propranolol might synergize.
More and more evidence for #propranolol being a possible help for #ptsd. I was on propranolol and I have long suspected the major permanent improvement in my #socialanxiety came from the exact mechanism they're suggesting, namely, disassociating the physical anxiety response from the trigger.
How it works: it's an adrenalin blocker. It drastically reduces fight-or-flight. I find it a lot more effective than benzos for general #anxiety and it's also not addictive.
Paper Moon
Mathrubhumi English
quangobaud
SleepyCatten
wolf of the wisp
PlanetMedicines
The Anxious Resistance
Muninn 🍃